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Association between air pollution and intrauterine mortality in Sao Paulo, Brazil.
Pereira LA, Loomis D, Conceicao GM, Braga AL, Arcas RM, Kishi HS, Singer JM, Bohm GM, Saldiva PH. Laboratorio de Poluicao Atmosferica Experimental, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brasil.

The associations among daily counts of intrauterine mortality and pollutant concentrations (NO2, SO2, CO, O3, and particulate matter (3/4)10 microm) were investigated for the period ranging from January 1991 to December 1992 in the city of Sao Paulo, Brazil. We used Poisson regression techniques, adjusted for season and weather. The association between intrauterine mortality and air pollution was strong for NO2 (coefficient = 0.0013/ microg/m3; p<0.01) but lesser for SO2 (coefficient = 0.0005/ microg/m3; p<0.10) and CO (coefficient = 0.0223/ppm; p<0.10). A significant association was observed when an index that combined these three pollutants was considered in the models instead of considering each pollutant individually (p<0.01). These associations exhibited a short time lag, not over 5 days. In addition, some evidence of fetal exposure to air pollution was obtained by disclosing a significant association between the levels of carboxyhemoglobin of blood sampled from the umbilical cord and ambient CO levels in children delivered by nonsmoking pregnant women in the period from May to July 1995. Our results suggest that air pollution in Sao Paulo may promote adverse health effects on fetuses.

Environ Health Perspect. 1998 Jun;106(6):325-9.

PMID: 9618348 [PubMed - indexed for MEDLINE]

See Also
Measuring impacts
Health impacts
Environmental impacts
Pereira LA, Loomis D, Conceicao GM, Braga AL, Arcas RM, Kishi HS, Singer JM, Bohm GM, Saldiva PH
Laboratorio de Poluicao Atmosferica Experimental, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brasil.
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E-mail: Clean_Air@worldbank.org