Clean Air Initiative: GlobalClean Air Initiative: AsiaIniciativa del Aire Limpio: América LatinaClean Air Initiative: Sub-Saharan Africa
Advanced Search
Countries
Topics
CAI Listserv
Air Quality Newsletters
Opportunities

Better Air Quality (BAQ) 2008
was held in Bangkok, Thailand
12-14 November 2008

Join the CAI-Asia Partnership

Effect of Particulate Air Pollution On Emergency Admissions for Myocardial Infarction: a Multi-city Case-crossover Analysis
Antonella Zanobetti and Joel Schwartz

Abstract

Recently, attention has focused on whether particulate air pollution is a specific trigger of myocardial infarction (MI). The results of several studies of single locations assessing the effects of ambient particular matter on the risk of MI have been disparate. We used a multicity case-crossover study to examine risk of emergency hospitalization associated with fine particulate matter (PM) with aerodynamic diameter < 10 µm (PM10) for > 300,000 MIs during 1985-1999 among elderly residents of 21 U.S. cities. We used time-stratified controls matched on day of the week or on temperature to detect possible residual confounding by weather. Overall, we found a 0.65% [95% confidence interval (CI), 0.3-1.0%] increased risk of hospitalization for MI per 10 µg/m3 increase in ambient PM10 concentration. Matching on apparent temperature yielded a 0.64% increase in risk (95% CI, 0.1-1.2%). We found that the effect size for PM10 doubled for subjects with a previous admission for chronic obstructive pulmonary disease or a secondary diagnosis of pneumonia, although these differences did not achieve statistical significance. There was a weaker indication of a larger effect on males but no evidence of effect modification by age or the other diagnoses. We also found that the shape of the exposure-response relationship between MI hospitalizations and PM10 is almost linear, but with a steeper slope at levels of PM10 < 50 µg/m3. We conclude that increased concentrations of ambient PM10 are associated with increased risk of MI among the elderly.

Read paper at Environment Health Perspective

air pollution, cardiovascular diseases, case-crossover, myocardial infarction, particulate matter
Quick Links

Who we are:
- CAI-Asia Center
- CAI-Asia Partnership
- Country Networks

Key documents:
- Annual Report 2008
- Fuel Roadmap
- Country Synthesis Reports
- Compendium | CitiesACT.org
- Benchmarking Report
- Quarterly Report (Center)
- Newsletters
................................more >>

Related Topics
Measuring impacts > Health impacts
Authors
Environmental Health Perspectives

Secretariat: CAI-Asia Center, 3510 Robinsons Equitable Tower, ADB Ave., Ortigas Center, Pasig City, Philippines 1605
Tel: +632 3952843 to 45 / Fax: +632 3952846